Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823531 | 0.84 | PDE7A (0.57) | PDE7AALDH1A1MEN1KMT2AHSP90AA1 | |
| SCHEMBL9823613 | 0.84 | PDE7A (0.44) | PDE7AALDH1A1CASRMEN1KMT2A | |
| SCHEMBL9823384 | 0.82 | ALDH1A1 (0.58) | PDE7AALDH1A1MEN1KMT2AHSP90AA1 | |
| SCHEMBL9823535 | 0.77 | NPC1 (0.57) | PDE7AALDH1A1MAPTNPC1PDE7B | |
| SCHEMBL9823879 | 0.73 | PDE7A (0.59) | PDE7AALDH1A1KMT2AMAPTNPC1 | |
| SCHEMBL10654255 | 0.72 | PARP14 (0.52) | PARP14 | |
| SCHEMBL9671188 | 0.70 | PDE7A (0.48) | PDE7AALDH1A1CASRMEN1KMT2A | |
| SCHEMBL9823310 | 0.69 | SMN1; SMN2 (0.52) | PDE7AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9823858 | 0.68 | SMN1; SMN2 (0.51) | ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL29832372 | 0.68 | PDE7A (0.69) | PDE7AALDH1A1MEN1KMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276826-B1 | 2-ALKYLSULFINYL-4 (3H)-QUINAZOLINONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4833144-A | ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-05-23 | — | — | US | disclosed |