Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9823531 | 0.92 | PDE7A (0.57) | ALDH1A1PDE7ARAB9AMDM2MEN1 | |
| SCHEMBL9823535 | 0.85 | NPC1 (0.57) | ALDH1A1SMN1; SMN2PDE7ARAB9AMAPT | |
| SCHEMBL9823612 | 0.84 | MEN1 (0.53) | ALDH1A1NPSR1SMN1; SMN2PDE7ARAB9A | |
| SCHEMBL9823326 | 0.82 | PDE7A (0.43) | ALDH1A1NPSR1PDE7ARAB9AMDM2 | |
| SCHEMBL9823879 | 0.80 | PDE7A (0.59) | ALDH1A1SMN1; SMN2PDE7ARAB9AMDM2 | |
| SCHEMBL9823310 | 0.78 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2PDE7ARAB9AMEN1 | |
| SCHEMBL9671260 | 0.76 | PDE7A (0.84) | ALDH1A1NPSR1SMN1; SMN2PDE7AMEN1 | |
| SCHEMBL9823858 | 0.75 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2RAB9AKMT2ALMNA | |
| SCHEMBL6483730 | 0.75 | PDE7A (0.58) | ALDH1A1SMN1; SMN2PDE7ARAB9AMEN1 | |
| SCHEMBL9823841 | 0.75 | ALDH1A1 (0.55) | ALDH1A1NPSR1SMN1; SMN2PDE7ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276826-B1 | 2-ALKYLSULFINYL-4 (3H)-QUINAZOLINONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4833144-A | ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0276826-A1 | 2-Alkylsulfinyl-4 (3H)-quinazolinone derivatives, processes for their preparation and pharmaceutical compositions | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |