SCHEMBL9823484

SCHEMBL9823484

NC(=O)CCC1CN(c2ccc(I)cc2)C(=O)O1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 16/20 0.50
F10 P00742 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10757225 0.85 GRM2 (0.54) GRM2F10
SCHEMBL3567695 0.84 GRM2 (0.47) GRM2F10
SCHEMBL3567689 0.84 GRM2 (0.47) GRM2F10
SCHEMBL2890876 0.83 CALML3 (0.47) GRM2F10
SCHEMBL5763614 0.83 CALML3 (0.47) GRM2F10
SCHEMBL2891483 0.81 MAOA (0.46) GRM2F10
SCHEMBL28812357 0.81 F10 (0.71) GRM2F10
SCHEMBL3323919 0.80 MAOA (0.58) GRM2F10
SCHEMBL3328770 0.80 F10 (0.63) GRM2F10
SCHEMBL3327082 0.80 MAOA (0.58) GRM2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0184170-B1 AMINOMETHYL OXOOXAZOLIDINYL BENZENE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-16 EP disclosed
US-4705799-A Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-10 US disclosed