SCHEMBL2890876

SCHEMBL2890876

NC(=O)CCC1CN(c2ccc(I)c(F)c2)C(=O)O1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CALML3 P27482 7/20 0.47
F10 P00742 1/20 0.46
MAOB P27338 5/20 0.45
MAOA P21397 4/20 0.45
LMNA P02545 1/20 0.45
PTGS1 P23219 1/20 0.45
SDHA P31040 1/20 0.45
GRM2 Q14416 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5763614 1.00 CALML3 (0.47) CALML3F10MAOBMAOALMNA
SCHEMBL6686605 0.88 F10 (0.57) CALML3F10MAOBMAOALMNA
SCHEMBL2891483 0.87 MAOA (0.46) CALML3F10MAOBMAOALMNA
SCHEMBL1556212 0.84 CALML3 (0.45) CALML3F10MAOBMAOALMNA
SCHEMBL1557789 0.84 CALML3 (0.45) CALML3F10MAOBMAOALMNA
SCHEMBL9823484 0.83 GRM2 (0.50) F10GRM2
SCHEMBL1394138 0.83 F10 (0.52) CALML3F10MAOBMAOALMNA
SCHEMBL5917588 0.83 F10 (0.52) CALML3F10MAOBMAOALMNA
SCHEMBL1036374 0.83 F10 (0.52) CALML3F10MAOBMAOALMNA
SCHEMBL1035579 0.83 CALML3 (0.65) CALML3MAOBMAOALMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US disclosed
EP-1799677-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS Ranbaxy Laboratories Limited (IN) 2007-06-27 EP disclosed
WO-2006038100-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2006-04-13 WO disclosed
US-6689779-B2 PYRIDINE OR PYRIMIDINE SUBSTITUTED; ANTIBACTERIAL ACTIVITY; LOW TOXICITY DONG A PHARM. CO., LTD. (KR) 2004-02-10 US disclosed
US-20030166620-A1 Novel oxazolidinone derivatives and a process for the preparation thereof DONG A PHARM. CO., LTD. (KR) 2003-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166620-A1 Novel oxazolidinone derivatives and a process for the preparation thereof OXA1L, ODC1, PDCD4 CALML3 4610/4885F10 2544/4885MAOB 593/4885
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS OXA1L, PDK4, MLYCD CALML3 3047/4885F10 1709/4885MAOB 2038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.