Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10629684 | 0.90 | GAA (0.38) | GAACDK1MAPTKDM4ENPC1 | |
| SCHEMBL9823783 | 0.87 | MAPT (0.40) | GAACDK1MAPTKDM4ENPC1 | |
| SCHEMBL10764375 | 0.82 | GAA (0.51) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10616134 | 0.81 | GAA (0.67) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10763019 | 0.80 | GAA (0.51) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10762380 | 0.80 | GAA (0.51) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10911982 | 0.80 | GAA (0.58) | GAACDK1MAPTTP53GLA | |
| SCHEMBL9822859 | 0.80 | GAA (0.53) | GAACDK1MAPTTP53GLA | |
| SCHEMBL9822976 | 0.80 | GAA (0.50) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10363689 | 0.78 | GAA (0.51) | GAACDK1MAPTTP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209230-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-02-27 | — | — | EP | claimed |
| US-4699647-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-10-13 | — | — | US | claimed |
| EP-0209230-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-01-21 | — | — | EP | claimed |
| EP-0209230-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4764205-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-08-16 | — | — | US | disclosed |
| US-4699647-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-10-13 | — | — | US | disclosed |
| EP-0209230-A1 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-01-21 | — | — | EP | disclosed |