Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1935538 | 0.85 | HPN (0.59) | HPNALDH1A1KDM4ETSHRSCN2A | |
| SCHEMBL9824170 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRSCN2AMEN1 | |
| SCHEMBL9824244 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL10854270 | 0.74 | HPN (0.68) | HPNALDH1A1KDM4ETSHRSCN2A | |
| SCHEMBL11120544 | 0.72 | KMT2A (0.63) | HPNALDH1A1KDM4ESCN2AMEN1 | |
| SCHEMBL6140131 | 0.72 | HPN (0.64) | HPNALDH1A1KDM4ETSHRSCN2A | |
| SCHEMBL9824921 | 0.72 | KDM4E (0.58) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL10429499 | 0.70 | MAPT (0.62) | HPNALDH1A1KDM4ESCN2AMEN1 | |
| SCHEMBL11273574 | 0.70 | HPN (0.57) | HPNALDH1A1KDM4ETSHRSCN2A | |
| SCHEMBL3868871 | 0.70 | HPN (0.60) | HPNALDH1A1KDM4ETSHRSCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4400202-A | N-m-Phenyl glutarimide derivatives and their use as herbicides | STAUFFER CHEMICAL COMPANY (US) | 1983-08-23 | — | — | US | disclosed |