Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2510494 | 0.82 | AR (0.52) | ALDH1A1KDM4EKMT2AMEN1DDB1 | |
| SCHEMBL9824921 | 0.82 | KDM4E (0.58) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL9823913 | 0.81 | HPN (0.52) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL10855744 | 0.79 | MEN1 (0.71) | ALDH1A1KDM4EKMT2AMEN1DDB1 | |
| SCHEMBL10859752 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL9824153 | 0.72 | LMNA (0.51) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL9824170 | 0.71 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL6798021 | 0.71 | L3MBTL1 (0.61) | ALDH1A1KDM4EKMT2AMEN1DDB1 | |
| SCHEMBL8883692 | 0.68 | L3MBTL1 (0.53) | ALDH1A1KDM4EKMT2AMEN1DDB1 | |
| SCHEMBL18913307 | 0.68 | KMT2A (0.80) | ALDH1A1KDM4EKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4595408-A | N-m-phenyl succinimide and glutarimide derivatives and their use as herbicides | STAUFFER CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |
| US-4400202-A | N-m-Phenyl glutarimide derivatives and their use as herbicides | STAUFFER CHEMICAL COMPANY (US) | 1983-08-23 | — | — | US | disclosed |