Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042587 | 0.98 | ALDH1A1 (0.61) | ALDH1A1ACHECYP19A1KDM4EHTR2B | |
| SCHEMBL11042509 | 0.98 | ALDH1A1 (0.61) | ALDH1A1ACHECYP19A1KDM4EHTR2B | |
| SCHEMBL11042549 | 0.85 | CYP19A1 (0.48) | ALDH1A1ACHECYP19A1HTR2BCSNK2A1 | |
| SCHEMBL2693532 | 0.84 | ALDH1A1 (0.61) | ALDH1A1ACHEKDM4ENPC1POLB | |
| SCHEMBL9823651 | 0.82 | CYP19A1 (0.53) | ALDH1A1ACHECYP19A1KDM4EHTR2B | |
| SCHEMBL9823776 | 0.81 | CYP19A1 (0.56) | ALDH1A1ACHECYP19A1KDM4EHTR2B | |
| SCHEMBL15609361 | 0.81 | ALDH1A1 (0.61) | ALDH1A1ACHEKDM4ENPC1POLB | |
| SCHEMBL11046608 | 0.81 | CYP19A1 (0.52) | ALDH1A1ACHECYP19A1KDM4EHTR2B | |
| SCHEMBL11046619 | 0.81 | CYP19A1 (0.52) | ALDH1A1ACHECYP19A1KDM4EHTR2B | |
| SCHEMBL11098546 | 0.78 | CYP19A1 (0.47) | ALDH1A1CYP19A1KDM4EHTR2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262873-B1 | N-TETRAZOLYL THIAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4879295-A | ANTIALLERGENS | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0262873-A1 | N-tetrazolyl thiazolecarboxamide derivatives and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1988-04-06 | — | — | EP | disclosed |
| US-4457936-A | ENZYME INHIBITORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-03 | — | — | US | disclosed |
| EP-0033151-B1 | HYDROXYPHENYL-THIAZOLE-THIAZOLINE AND -THIAZOLIDINE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THESE COMPOUNDS FOR USE IN INFLUENCING THE COLLAGEN METABOLISM | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-05-02 | — | — | EP | disclosed |
| EP-0033151-A1 | Hydroxyphenyl-thiazole-thiazoline and -thiazolidine carboxylic acids, process for their preparation and these compounds for use in influencing the collagen metabolism | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-05 | — | — | EP | disclosed |