Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824016 | 0.92 | ALDH1A1 (0.38) | ALDH1A1RAB9ALMNASMN1; SMN2HDAC3 | |
| SCHEMBL9824039 | 0.91 | SMN1; SMN2 (0.40) | ALDH1A1RAB9AGAALMNATDP1 | |
| SCHEMBL10338291 | 0.90 | NPSR1 (0.35) | ALDH1A1RAB9AGAALMNAPOLB | |
| SCHEMBL9374218 | 0.89 | NPSR1 (0.34) | ALDH1A1RAB9ALMNAPOLBSMN1; SMN2 | |
| SCHEMBL9374243 | 0.88 | POLB (0.33) | ALDH1A1LMNAPOLBTDP1HDAC3 | |
| SCHEMBL9371923 | 0.88 | OPRK1 (0.38) | ALDH1A1POLBMAPT | |
| SCHEMBL9824287 | 0.84 | GAA (0.37) | ALDH1A1GAALMNAPOLBTDP1 | |
| SCHEMBL9824445 | 0.77 | NPSR1 (0.39) | RAB9ALMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL9824718 | 0.76 | NPSR1 (0.35) | ALDH1A1GAATDP1SMN1; SMN2MAPT | |
| SCHEMBL9824163 | 0.75 | KMT2A (0.35) | ALDH1A1RAB9AGAAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273417-B1 | THIADIAZABICYCLONONANE DERIVATIVES AND HERBICIDAL COMPOSITIONS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-4906279-A | Thiadiazabicyclononane derivatives and herbicidal composition | KUMIAI CHEMICAL INDUSTRY CO. (JP) | 1990-03-06 | — | — | US | disclosed |