SCHEMBL98244

SCHEMBL98244

OCc1ccc(Br)cc1Br

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.48
PTGDR2 Q9Y5Y4 1/20 0.43
PYCR1 P32322 1/20 0.43
TDP1 Q9NUW8 2/20 0.41
MAPK1 P28482 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HSP90AA1 P07900 1/20 0.41
TLR9 Q9NR96 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
HPGD P15428 2/20 0.37
KMT2A Q03164 2/20 0.37
CHEK1 O14757 1/20 0.37
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 1/20 0.36
HTT P42858 1/20 0.36
ATM Q13315 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29417721 0.82 PTGDR2 (0.48) ALOX15PTGDR2MAPK1ALDH1A1SLC6A2
SCHEMBL795719 0.82 PTGDR2 (0.48) ALOX15PTGDR2MAPK1ALDH1A1SLC6A2
SCHEMBL4798355 0.81 ALOX15 (0.44) ALOX15PTGDR2PYCR1TDP1MAPK1
SCHEMBL1047305 0.80 PTGDR2 (0.47) ALOX15PTGDR2TDP1MAPK1ALDH1A1
SCHEMBL17868453 0.80 PTGDR2 (0.43) ALOX15PTGDR2ALDH1A1SLC6A2SLC6A4
SCHEMBL7955333 0.79 ALOX15 (0.46) ALOX15PYCR1TDP1MAPK1ALDH1A1
SCHEMBL11918441 0.78 ALOX15 (0.46) ALOX15PTGDR2ALDH1A1SLC6A2SLC6A4
SCHEMBL31395060 0.78 TYR (0.44) ALOX15TDP1KMT2AMAPTMEN1
SCHEMBL2970964 0.78 EGFR (0.43) SLC6A2SLC6A4TSHRP4HB
SCHEMBL11480765 0.78 TYR (0.44) ALOX15TDP1KMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113480410-A Synthetic method of 2, 4-dibromobenzyl alcohol 南京伊派森化学科技有限公司 2021-10-08 CN claimed
US-20230149414-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-05-18 US disclosed
US-20230149414-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-05-18 US disclosed
US-20230149414-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-05-18 US disclosed
CN-115484948-A Compound and use thereof 福宏治疗公司 2022-12-16 CN disclosed
EP-4096657-A1 COMPOUNDS AND USES THEREOF Foghorn Therapeutics Inc. (US) 2022-12-07 EP disclosed
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed
EP-4036100-A1 SPIROKETAL DERIVATIVES AND PROCESS FOR PREPARATION OF SPIROKETAL DERIVATIVES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-08-03 EP disclosed
EP-3971191-A1 BORON-CONTAINING SMALL MOLECULES Bill And Melinda Gates Foundation (US) 2022-03-23 EP disclosed
EP-3170834-B1 CRYSTALLINE FORMS OF (1S,3'R,4'S,5'S,6'R)-6-[(4-ETHYLPHENYL)METHYL]-3',4',5',6'-TETRAHYDRO-6'-(HYDROXYMETHYL)SPIRO[ISOBENZOFURAN-1(3H) 2'-[2H]PYRAN]-3',4',5'-TRIOL CHUGAI PHARMACEUTICAL CO LTD (JP) 2022-02-09 EP disclosed
EP-1298176-A2 Stacked film insulating film and substrate for semiconductor JSR Corporation (JP) 2003-04-02 EP disclosed
US-20020172652-A1 Composition for film formation and material for insulating film formation JSR CORPORATION (JP) 2002-11-21 US disclosed
US-6476021-B1 Compounds having cGMP-PDE inhibitory effect MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2002-11-05 US disclosed
EP-1245638-A1 Composition for insulating film formation JSR Corporation (JP) 2002-10-02 EP disclosed
US-20020064953-A1 Chemical mechanical polishing stopper film, process for producing the same, and method of chemical mechanical polishing JSR CORPORATION (JP) 2002-05-30 US disclosed
EP-1188807-A2 Chemical mechanical polishing stopper film, process for producing the same, and method of chemical mechanical polishing JSR Corporation (JP) 2002-03-20 EP disclosed
EP-0956312-B1 PROCESS FOR PRODUCING PHENYLENE-CONTAINING POLYMER AND FILM-FORMING MATERIAL JSR CORP (JP) 2001-10-10 EP disclosed
US-6300465-B1 Process for producing phenylene-containing polymer and film-forming material JSR CORPORATION (JP) 2001-10-09 US disclosed
EP-1048666-A1 NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2000-11-02 EP disclosed
EP-0198687-A2 Alpha-polyhaloketoximes ROHM AND HAAS COMPANY (US) 1986-10-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149414-A1 COMPOUNDS AND USES THEREOF VHL, CLN6, TFEB ALOX15 3537/4885PTGDR2 4260/4885PYCR1 3154/4885
US-20020172652-A1 Composition for film formation and material for insulating film formation VCL, BMI1, PUF60 ALOX15 1206/4885PTGDR2 4168/4885PYCR1 2866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.