Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824509 | 0.97 | HDAC3 (0.59) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL10150375 | 0.89 | BCHE (0.52) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL24685749 | 0.87 | HDAC3 (0.50) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL16727723 | 0.87 | HDAC1 (0.63) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL11273441 | 0.86 | ALDH1A1 (0.57) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL8850877 | 0.83 | HDAC3 (0.59) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL8642987 | 0.83 | HDAC3 (0.59) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL18546018 | 0.83 | TSHR (0.46) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL1830778 | 0.82 | HDAC3 (0.63) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL10150374 | 0.82 | ALDH1A1 (0.57) | HDAC3HDAC1HDAC2HDAC8NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199963-B1 | ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES | ABBOTT LABORATORIES (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0199963-A1 | Ethosuximide assay tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1986-11-05 | — | — | EP | disclosed |