Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430396 | 0.85 | TSHR (0.62) | ALDH1A1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL9824734 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2AGAAPOLB | |
| SCHEMBL7905669 | 0.81 | HTR2A (0.56) | ALDH1A1MAPTKMT2AGAARAB9A | |
| SCHEMBL11306225 | 0.80 | MAPT (0.51) | ALDH1A1MAPTKMT2AGAAMEN1 | |
| SCHEMBL10309729 | 0.78 | TSHR (0.70) | MAPTKMT2AMEN1POLBNPC1 | |
| SCHEMBL21652695 | 0.77 | MGAM (0.62) | ALDH1A1MAPTKMT2AGAAMEN1 | |
| SCHEMBL2533623 | 0.77 | MAPT (0.63) | ALDH1A1MAPTKMT2AGAAMEN1 | |
| SCHEMBL10048327 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2AGAAMEN1 | |
| SCHEMBL13932524 | 0.75 | ALDH1A1 (0.66) | ALDH1A1MAPTKMT2AGAAMEN1 | |
| SCHEMBL3134365 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261442-B1 | MALONIC ACID DERIVATIVES | NIHON NOHYAKU CO., LTD. (JP) | 1991-11-13 | — | — | EP | claimed |