Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1555636 | 0.88 | ALDH1A1 (0.59) | HTR2AALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL27787118 | 0.85 | GAA (0.60) | HTR2AALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL9344653 | 0.84 | LMNA (0.57) | HTR2AALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL10801173 | 0.84 | HTR2A (0.67) | HTR2AALDH1A1MAPTL3MBTL1RAB9A | |
| Malonic Acid SCHEMBL8982152 | 0.82 | ALDH1A1 (0.54) | HTR2AALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL5765803 | 0.82 | ALDH1A1 (0.57) | HTR2AALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL7982908 | 0.82 | HTR2A (0.52) | HTR2AALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL11094410 | 0.82 | ALDH1A1 (0.56) | HTR2AALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL9824533 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTGAAMAPK1RAB9A | |
| SCHEMBL1554845 | 0.81 | ALDH1A1 (0.55) | HTR2AALDH1A1MAPTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204277-B1 | TREATING DIABETES | JAPAN TOBACCO INC. (JP) | 2001-03-20 | — | — | US | disclosed |
| CN-1233241-A | Propionic acid derivatives and uses thereof | JAPAN TOBACCO INC (JP) | 1999-10-27 | — | — | CN | disclosed |
| EP-0930299-A1 | PROPIONIC ACID DERIVATIVES AND APPLICATIONS THEREOF | Japan Tobacco Inc. (JP) | 1999-07-21 | — | — | EP | disclosed |