Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9691718 | 0.99 | HTT (0.45) | HTTNPC1RAB9AMTNR1ADRD2 | |
| SCHEMBL567584 | 0.90 | DRD2 (0.52) | DRD2 | |
| Hydrochloric Acid SCHEMBL9691966 | 0.89 | DRD2 (0.51) | DRD2 | |
| SCHEMBL9824816 | 0.85 | MTNR1A (0.46) | HTTNPC1RAB9AMTNR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9825009 | 0.84 | CYP1A2 (0.45) | HTTNPC1RAB9AMTNR1ADRD2 | |
| SCHEMBL9692857 | 0.82 | MALT1 (0.44) | MTNR1ADRD2 | |
| SCHEMBL9692552 | 0.81 | HTT (0.47) | HTTNPC1RAB9AMTNR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9692852 | 0.81 | MALT1 (0.44) | MTNR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9692396 | 0.80 | HTT (0.46) | HTTNPC1RAB9AMTNR1ADRD2 | |
| SCHEMBL9825622 | 0.76 | HTT (0.46) | HTTNPC1RAB9AMTNR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252005-B1 | HYDROGENATED 1-BENZOOXACYCLOALKYL-PYRIDINE CARBOXYLIC-ACID COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | claimed |