Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743364 | 0.83 | ALDH1A1 (0.46) | POLBTDP1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL465595 | 0.81 | ALDH1A1 (0.63) | POLBTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL8179624 | 0.77 | POLB (0.59) | POLBTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL8167111 | 0.77 | HDAC1 (0.58) | POLBTDP1L3MBTL1ALDH1A1HDAC1 | |
| SCHEMBL9618235 | 0.76 | HDAC1 (0.56) | POLBTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL8174284 | 0.75 | ALDH1A1 (0.46) | ALDH1A1RAB9ANPC1SMN1; SMN2HDAC1 | |
| SCHEMBL1004360 | 0.75 | MLYCD (0.62) | L3MBTL1ALDH1A1HDAC1HDAC6HPGD | |
| SCHEMBL10719119 | 0.75 | ABCB1 (0.45) | POLBTDP1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL8177791 | 0.75 | POLB (0.56) | POLBTDP1L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL9277393 | 0.74 | TDP1 (0.50) | POLBTDP1L3MBTL1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |