Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 10/20 | 0.58 |
| ▸ | PLG | P00747 | 10/20 | 0.58 |
| ▸ | F2 | P00734 | 9/20 | 0.58 |
| ▸ | F12 | P00748 | 6/20 | 0.58 |
| ▸ | KLK1 | P06870 | 3/20 | 0.58 |
| ▸ | F10 | P00742 | 3/20 | 0.58 |
| ▸ | C1R | P00736 | 2/20 | 0.58 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.58 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.58 |
| ▸ | MLNR | O43193 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | HPN | P05981 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
| ▸ | C1S | P09871 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824643 | 0.96 | FTO (0.64) | PRSS1PLGF2F12KLK1 | |
| Hydrochloric Acid SCHEMBL9825728 | 0.95 | FTO (0.63) | PRSS1PLGF2F12KLK1 | |
| SCHEMBL14294845 | 0.86 | PRSS1 (0.59) | PRSS1PLGF2F12KLK1 | |
| SCHEMBL7406688 | 0.83 | PRSS1 (0.62) | PRSS1PLGF2F12KLK1 | |
| Nafamostat SCHEMBL16069975 | 0.83 | PRSS1 (0.64) | PRSS1PLGF2F12KLK1 | |
| Nafamostat SCHEMBL135503 | 0.83 | PRSS1 (0.64) | PRSS1PLGF2F12KLK1 | |
| Nafamostat SCHEMBL29429445 | 0.83 | PRSS1 (0.64) | PRSS1PLGF2F12KLK1 | |
| Nafamostat SCHEMBL29429443 | 0.83 | PRSS1 (0.64) | PRSS1PLGF2F12KLK1 | |
| SCHEMBL25633204 | 0.83 | PRSS1 (0.76) | PRSS1PLGF2F12KLK1 | |
| Nafamostat SCHEMBL3302794 | 0.82 | PRSS1 (0.63) | PRSS1PLGF2F12KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0190356-B1 | NOVEL AMIDINE COMPOUNDS | TORII & CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| US-4820730-A | ANTI-TRYPSIN, ANTI-PLASMIN, ANTI-THROMBIN, ANTI-KALLIKREIN ACTIVITY | TORII & CO., LTD. (JP) | 1989-04-11 | — | — | US | disclosed |
| US-4777182-A | ENZYME, HORMONE, COMPLEMENT INHIBITORS | TORII & CO., LTD. (JP) | 1988-10-11 | — | — | US | disclosed |
| EP-0190356-A1 | NOVEL AMIDINE COMPOUNDS | TORII & CO., LTD. (JP) | 1986-08-13 | — | — | EP | disclosed |