Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825994 | 0.90 | ABCB1 (0.53) | ABCB1KMT2AHDAC8HDAC3HDAC1 | |
| SCHEMBL9826217 | 0.86 | GAA (0.53) | ABCB1HPGDTDP1KMT2AHDAC3 | |
| SCHEMBL9824960 | 0.86 | HDAC1 (0.46) | ABCB1KMT2AHDAC8HDAC3HDAC1 | |
| SCHEMBL9825740 | 0.83 | TSHR (0.55) | KMT2AHDAC8HDAC3HDAC1HDAC2 | |
| SCHEMBL9824771 | 0.81 | HDAC1 (0.48) | HPGDKMT2AHDAC8HDAC3HDAC1 | |
| SCHEMBL10719402 | 0.78 | ABCB1 (0.74) | KCNK3ABCB1HPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL9618235 | 0.77 | HDAC1 (0.56) | HPGDTDP1KMT2AHDAC8HDAC3 | |
| SCHEMBL9824801 | 0.77 | HDAC1 (0.44) | HPGDKMT2AHDAC8HDAC3HDAC1 | |
| SCHEMBL9824994 | 0.77 | LMNA (0.48) | HPGD | |
| SCHEMBL7775392 | 0.76 | ABCB1 (0.62) | ABCB1HPGDSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |