Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824994 | 0.86 | LMNA (0.48) | ALDH1A1HPGDLMNARAB9A | |
| SCHEMBL9825135 | 0.83 | RAB9A (0.46) | HDAC1HDAC3HDAC2HDAC6HDAC8 | |
| SCHEMBL9824771 | 0.79 | HDAC1 (0.48) | HDAC1HDAC3HDAC2HDAC6HDAC8 | |
| SCHEMBL10718314 | 0.78 | POLB (0.57) | — | |
| SCHEMBL9826073 | 0.78 | FLT1 (0.47) | HDAC1HDAC3HDAC2HDAC6HDAC8 | |
| SCHEMBL9825994 | 0.78 | ABCB1 (0.53) | HDAC1HDAC3HDAC2HDAC6HDAC8 | |
| SCHEMBL9825272 | 0.77 | KCNK3 (0.52) | HDAC1HDAC3HDAC2HDAC6HDAC8 | |
| Hydrochloric Acid SCHEMBL8166396 | 0.77 | POLB (0.56) | — | |
| SCHEMBL9824960 | 0.77 | HDAC1 (0.46) | HDAC1HDAC3HDAC2HDAC6HDAC8 | |
| SCHEMBL9825740 | 0.76 | TSHR (0.55) | HDAC1HDAC3HDAC2HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |