Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825697 | 0.75 | ALDH1A1 (0.47) | HTTNPC1RAB9AKMT2AMAPT | |
| SCHEMBL458598 | 0.71 | GAA (0.54) | GAAHTTTSHRSMN1; SMN2NPC1 | |
| SCHEMBL642316 | 0.70 | GAA (0.72) | GAAHTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL31481191 | 0.70 | GAA (0.49) | GAAHTTTSHRSMN1; SMN2NPC1 | |
| SCHEMBL11597346 | 0.70 | GAA (0.53) | GAAHTTTSHRSMN1; SMN2NPC1 | |
| SCHEMBL11293119 | 0.70 | GAA (0.85) | GAAHTTTSHRSMN1; SMN2KMT2A | |
| SCHEMBL9826226 | 0.69 | MEN1 (0.49) | GAATSHRSMN1; SMN2KMT2ACES2 | |
| Ethylene SCHEMBL8378406 | 0.68 | GAA (0.68) | GAAHTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL2666138 | 0.67 | GAA (1.00) | GAAHTTSMN1; SMN2KMT2AMAPT | |
| SCHEMBL31481263 | 0.67 | GAA (0.49) | GAAHTTTSHRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203743-B1 | OXOTHIAZOLIDINE COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |
| US-4764514-A | COGNITIONACTIVATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-16 | — | — | US | disclosed |
| EP-0203743-A1 | Oxothiazolidine compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-03 | — | — | EP | disclosed |