Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826183 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPTRAB9AHPGD | |
| SCHEMBL9825223 | 0.83 | HPGD (0.50) | ALDH1A1KMT2ACYP1A2MAPTNPC1 | |
| SCHEMBL9825330 | 0.79 | KMT2A (0.58) | ALDH1A1KMT2ACYP1A2MAPTCYP2C19 | |
| SCHEMBL9826226 | 0.79 | MEN1 (0.49) | KMT2AHPGDMEN1GSK3BSIGMAR1 | |
| SCHEMBL8417169 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KMT2ACYP1A2MAPTCYP2C19 | |
| SCHEMBL27909744 | 0.72 | KMT2A (0.44) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL7338840 | 0.72 | ALDH1A1 (0.61) | ALDH1A1KMT2ACYP1A2MAPTCYP2C19 | |
| SCHEMBL30063016 | 0.71 | ALDH1A1 (0.55) | ALDH1A1KMT2ACYP1A2MAPTCYP2C19 | |
| SCHEMBL1002469 | 0.69 | CYP1A2 (0.64) | ALDH1A1KMT2ACYP1A2MAPTCYP2C19 | |
| SCHEMBL6960124 | 0.68 | SMN1; SMN2 (0.63) | ALDH1A1KMT2ACYP1A2MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203743-B1 | OXOTHIAZOLIDINE COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |
| US-4764514-A | COGNITIONACTIVATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-16 | — | — | US | disclosed |
| EP-0203743-A1 | Oxothiazolidine compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-03 | — | — | EP | disclosed |