Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | RORA | P35398 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | RORB | Q92753 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825790 | 1.00 | GPR3 (0.50) | GPR3PSMB5HSD11B1TLR8RORA | |
| SCHEMBL9826442 | 0.98 | GPR3 (0.48) | GPR3PSMB5HSD11B1TLR8RORA | |
| SCHEMBL9826026 | 0.88 | CNR1 (0.41) | PSMB5TLR8 | |
| SCHEMBL9826023 | 0.85 | GPR3 (0.44) | GPR3PSMB5HSD11B1TLR8RORA | |
| SCHEMBL9825795 | 0.85 | GPR3 (0.44) | GPR3PSMB5HSD11B1TLR8RORA | |
| SCHEMBL9826492 | 0.85 | GPR3 (0.44) | GPR3PSMB5HSD11B1TLR8RORA | |
| SCHEMBL9824789 | 0.84 | RARB (0.44) | GPR3HTR2A | |
| SCHEMBL9825219 | 0.81 | GPR3 (0.41) | GPR3TLR8RORARORCRORB | |
| SCHEMBL9825625 | 0.81 | GPR3 (0.41) | GPR3TLR8RORARORCRORB | |
| SCHEMBL16698681 | 0.81 | HSD11B1 (0.47) | GPR3PSMB5HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037575-A | Photostability | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0187015-B1 | SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | MITSUBISHI KASEI CORPORATION (JP) | 1991-05-29 | — | — | EP | disclosed |