Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825223 | 0.83 | HPGD (0.50) | ALDH1A1HPGDMAPTCES2CES1 | |
| SCHEMBL9825697 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTRAB9AKMT2A | |
| SCHEMBL9826226 | 0.80 | MEN1 (0.49) | HPGDMGLLCES2CES1SMN1; SMN2 | |
| SCHEMBL9825330 | 0.80 | KMT2A (0.58) | ALDH1A1HPGDMAPTPOLBCES2 | |
| SCHEMBL8543824 | 0.70 | MITF (0.64) | ALDH1A1HPGDHSD17B10MAPTPOLB | |
| SCHEMBL11481475 | 0.69 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10MAPTPOLB | |
| SCHEMBL8539282 | 0.69 | MITF (0.67) | ALDH1A1HPGDHSD17B10MAPTPOLB | |
| SCHEMBL8089825 | 0.68 | MAPT (0.65) | ALDH1A1MAPTMGLLKMT2A | |
| SCHEMBL29279199 | 0.68 | HTT (0.49) | ALDH1A1HPGDHSD17B10MAPTPOLB | |
| SCHEMBL10833177 | 0.68 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203743-B1 | OXOTHIAZOLIDINE COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |
| US-4764514-A | COGNITIONACTIVATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-16 | — | — | US | disclosed |
| EP-0203743-A1 | Oxothiazolidine compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-03 | — | — | EP | disclosed |