Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 5/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP4 | P49662 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17434501 | 0.81 | CASP1 (0.46) | KMT2AMEN1MMP2MAPTALDH1A1 | |
| SCHEMBL9826702 | 0.80 | F2 (0.47) | F2F10LMNAMAPK1 | |
| SCHEMBL9826121 | 0.75 | KMT2A (0.57) | KMT2AMEN1MMP2L3MBTL1MAPT | |
| SCHEMBL31444744 | 0.73 | ATM (0.45) | KMT2AMEN1F2F10MAPT | |
| SCHEMBL17434397 | 0.73 | KMT2A (0.67) | KMT2AMEN1MMP2L3MBTL1MAPT | |
| SCHEMBL7475333 | 0.72 | KMT2A (0.46) | KMT2AMEN1L3MBTL1NR1H2NR1H3 | |
| SCHEMBL9453682 | 0.72 | TACR1 (0.51) | MMP2MAPTALDH1A1LMNACASP1 | |
| SCHEMBL30806262 | 0.71 | CASP1 (0.52) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL9462346 | 0.70 | F2 (0.42) | F2F10 | |
| SCHEMBL30806728 | 0.69 | TSHR (0.51) | KMT2AMEN1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283036-B1 | BENZOXAZINE DERIVATIVES AND PROCESSES FOR PREPARATION THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4824833-A | ANTIDIABETIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| EP-0283036-A1 | Benzoxazine derivatives and processes for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |