Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.47 |
| ▸ | F10 | P00742 | 7/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825925 | 0.80 | KMT2A (0.46) | F2F10LMNAMAPK1 | |
| SCHEMBL17434537 | 0.79 | TSHR (0.41) | F2F10GSK3BTSHRUSP2 | |
| SCHEMBL10129667 | 0.76 | PDE3B (0.50) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL10129678 | 0.76 | PDE3B (0.50) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL9462346 | 0.74 | F2 (0.42) | F2F10CES2MDM2RIPK1 | |
| SCHEMBL3602608 | 0.73 | REN (0.37) | — | |
| SCHEMBL26630176 | 0.73 | GSK3B (0.52) | CES2CHEK1AURKADAPK3JAK2 | |
| SCHEMBL9826530 | 0.72 | BRD4 (0.49) | GSK3BTSHRUSP2MAPK1 | |
| SCHEMBL6748454 | 0.71 | F2 (0.54) | F2F10TSHR | |
| SCHEMBL3602611 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283036-B1 | BENZOXAZINE DERIVATIVES AND PROCESSES FOR PREPARATION THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4824833-A | ANTIDIABETIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| EP-0283036-A1 | Benzoxazine derivatives and processes for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |