Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824662 | 0.91 | ATM (0.44) | KMT2AMEN1ATMLMNAADRB2 | |
| SCHEMBL9824991 | 0.90 | ATM (0.48) | KMT2AMEN1ATMLMNAADRB2 | |
| SCHEMBL9825202 | 0.88 | ADRB2 (0.43) | KMT2AMEN1ATMLMNAADRB2 | |
| Bromide SCHEMBL10775334 | 0.88 | ATM (0.42) | KMT2AMEN1ATMLMNAADRB2 | |
| SCHEMBL9824815 | 0.88 | ATM (0.42) | KMT2AMEN1ATMLMNAADRB2 | |
| SCHEMBL9826041 | 0.88 | ADRB2 (0.43) | KMT2AMEN1ATMLMNAADRB2 | |
| Hydrochloric Acid SCHEMBL9825467 | 0.88 | ATM (0.42) | KMT2AMEN1ATMLMNAADRB2 | |
| SCHEMBL9825143 | 0.88 | ATM (0.42) | ATMLMNAADRB2ADRB1ADRB3 | |
| SCHEMBL9825259 | 0.88 | MEN1 (0.46) | KMT2AMEN1ATMLMNAADRB2 | |
| SCHEMBL9825260 | 0.88 | ADRB2 (0.42) | KMT2AMEN1ATMLMNAADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167371-B1 | DIHYDROPYRIDINE COMPOUNDS, THEIR PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |