Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825202 | 1.00 | ADRB2 (0.43) | ADRB2ADRB1ADRB3ATMMEN1 | |
| SCHEMBL9825260 | 0.99 | ADRB2 (0.42) | ADRB2ADRB1ADRB3ATMMEN1 | |
| Hydrochloric Acid SCHEMBL9824900 | 0.99 | ADRB2 (0.44) | ADRB2ADRB1ADRB3ATMMEN1 | |
| SCHEMBL10903807 | 0.95 | ATM (0.47) | ADRB2ADRB1ADRB3ATMMEN1 | |
| SCHEMBL9824996 | 0.95 | ATM (0.47) | ADRB2ADRB1ADRB3ATMMEN1 | |
| SCHEMBL9825159 | 0.94 | MAPT (0.42) | ADRB2ADRB1ADRB3ATMMEN1 | |
| SCHEMBL9825035 | 0.94 | ADRB2 (0.43) | ADRB2ADRB1ADRB3ATMMEN1 | |
| SCHEMBL9825289 | 0.92 | ADRB2 (0.42) | ADRB2ADRB1ADRB3ATMMEN1 | |
| SCHEMBL9825165 | 0.91 | ADRB1 (0.42) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL9825462 | 0.89 | ADRB1 (0.43) | ADRB2ADRB1ADRB3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167371-B1 | DIHYDROPYRIDINE COMPOUNDS, THEIR PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-03-06 | — | — | EP | claimed |