Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 8/20 | 0.45 |
| ▸ | GLA | P06280 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788354 | 0.72 | KMT2A (0.55) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29456286 | 0.70 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1907032 | 0.70 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27490294 | 0.69 | ALDH1A1 (0.45) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1906111 | 0.69 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21233347 | 0.69 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9118620 | 0.69 | ALDH1A1 (0.49) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL822672 | 0.68 | NR1H2 (0.47) | KDM4EALDH1A1NPC1RAB9AHDAC1 | |
| SCHEMBL10475743 | 0.68 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12596380 | 0.68 | KDM4E (0.65) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165753-B1 | HERBICIDAL THIOPHENESULFONAMIDES AND PYRIDINESULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| US-4723988-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-02-09 | — | — | US | disclosed |
| US-4684393-A | PLATN GROWTH REGULATORS | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1987-08-04 | — | — | US | disclosed |
| EP-0165753-A2 | Herbicidal thiophenesulfonamides and pyridinesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-12-27 | — | — | EP | disclosed |