Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908280 | 0.77 | KDM4E (0.47) | ALDH1A1NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL2040756 | 0.74 | KDM4E (0.45) | ALDH1A1NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL27490293 | 0.73 | KDM4E (0.48) | ALDH1A1NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL9825980 | 0.69 | KDM4E (0.46) | ALDH1A1NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL12596380 | 0.67 | KDM4E (0.65) | ALDH1A1NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL1907032 | 0.66 | KDM4E (0.46) | ALDH1A1NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL16363152 | 0.65 | KDM4E (0.56) | ALDH1A1NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL1906111 | 0.65 | KDM4E (0.45) | ALDH1A1NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL9118620 | 0.65 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL1234818 | 0.65 | KDM4E (0.61) | ALDH1A1NPC1RAB9AKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1177350-A | Imidazole derivatives and pharmaceutical compositions thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1998-03-25 | — | — | CN | disclosed |