Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827347 | 0.87 | NPC1 (0.39) | SMN1; SMN2ALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL9826788 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL9827332 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL9826207 | 0.68 | MAPK1 (0.34) | — | |
| SCHEMBL11392114 | 0.67 | — | — | |
| SCHEMBL20359 | 0.67 | — | — | |
| SCHEMBL17547305 | 0.66 | — | — | |
| SCHEMBL9826555 | 0.66 | KDM4E (0.33) | — | |
| SCHEMBL31241343 | 0.66 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL9827817 | 0.64 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301613-B1 | THIAZOLE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1991-07-10 | — | — | EP | disclosed |
| US-4889863-A | NONPHYTOTOXIC; SEEDS, SOILS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1989-12-26 | — | — | US | disclosed |
| EP-0301613-A1 | Thiazole compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-02-01 | — | — | EP | disclosed |