Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826555 | 0.91 | KDM4E (0.33) | KDM4EHSD17B10 | |
| SCHEMBL9826495 | 0.88 | KDM4E (0.33) | KDM4EHSD17B10 | |
| SCHEMBL9827347 | 0.81 | NPC1 (0.39) | — | |
| SCHEMBL10567472 | 0.81 | — | — | |
| SCHEMBL9826435 | 0.78 | KDM4E (0.33) | KDM4E | |
| SCHEMBL9826788 | 0.73 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL11383532 | 0.69 | — | — | |
| SCHEMBL9826067 | 0.68 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL10572170 | 0.68 | CDC7 (0.33) | MAPK1RECQLKDM4EHSD17B10 | |
| SCHEMBL9827037 | 0.67 | KDR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301613-B1 | THIAZOLE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1991-07-10 | — | — | EP | disclosed |
| US-4889863-A | NONPHYTOTOXIC; SEEDS, SOILS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1989-12-26 | — | — | US | disclosed |
| EP-0301613-A1 | Thiazole compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-02-01 | — | — | EP | disclosed |