Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10761583 | 0.85 | HTR2C (0.49) | HTR2CHTR2AHTR2BDRD2CA12 | |
| SCHEMBL5801397 | 0.81 | HTR2C (0.46) | HTR2CHTR2AHTR2BDRD2CA12 | |
| SCHEMBL13381007 | 0.80 | HTR2C (0.45) | HTR2CHTR2AHTR2BDRD2CA12 | |
| SCHEMBL11629567 | 0.79 | HTR2C (0.44) | HTR2CHTR2AHTR2BDRD2CA12 | |
| SCHEMBL13381250 | 0.76 | DRD2 (0.46) | HTR2CHTR2AHTR2BDRD2MEN1 | |
| SCHEMBL13381276 | 0.76 | CYP19A1 (0.43) | HTR2CHTR2AHTR2BDRD2CA12 | |
| SCHEMBL935859 | 0.75 | HTR2C (0.50) | HTR2CHTR2AHTR2BDRD2CA12 | |
| SCHEMBL6484237 | 0.75 | HTR2C (0.50) | HTR2CHTR2AHTR2BDRD2CA12 | |
| SCHEMBL29474981 | 0.75 | HTR2C (0.50) | HTR2CHTR2AHTR2BDRD2CA12 | |
| SCHEMBL13380953 | 0.74 | HTR2C (0.43) | HTR2CHTR2AHTR2BDRD2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228887-B1 | DIOXANE HEXENOIC ACIDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-24 | — | — | EP | disclosed |