Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11629567 | 0.84 | HTR2C (0.44) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL10761583 | 0.83 | HTR2C (0.49) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL13380953 | 0.83 | HTR2C (0.43) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL14272740 | 0.83 | HTR2C (0.43) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL13381276 | 0.81 | CYP19A1 (0.43) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL13381250 | 0.81 | DRD2 (0.46) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL5801397 | 0.80 | HTR2C (0.46) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL9826178 | 0.80 | HTR2C (0.46) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL13381350 | 0.79 | DRD2 (0.47) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL935859 | 0.77 | HTR2C (0.50) | HTR2CHTR2AHTR2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081693-A1 | THIADIAZOLE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081693-A1 | THIADIAZOLE COMPOUND AND USE THEREOF | NR2C2, NR4A3, NR0B2 | HTR2C 106/4885HTR2A 857/4885HTR2B 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.