Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019141 | 0.82 | — | — | |
| SCHEMBL18545242 | 0.71 | MAP3K14 (0.33) | CRBNMAP3K14 | |
| SCHEMBL455753 | 0.71 | — | — | |
| SCHEMBL5390017 | 0.71 | — | — | |
| SCHEMBL20827756 | 0.71 | MAP3K14 (0.33) | CRBNCYP19A1MAP3K14 | |
| SCHEMBL3628793 | 0.71 | MAP3K14 (0.33) | CRBNMAP3K14 | |
| SCHEMBL5390855 | 0.67 | MAP3K14 (0.36) | MAP3K14 | |
| SCHEMBL9463682 | 0.67 | CRBN (0.39) | CRBNCYP19A1MAP3K14 | |
| SCHEMBL5909395 | 0.65 | ALDH1A1 (0.31) | — | |
| SCHEMBL5397907 | 0.65 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983611-A | TREATING A STOMACH MOTILITY DISTURBANCE | KALI-CHEMIE PHARMA GMBH (DE) | 1991-01-08 | — | — | US | claimed |
| EP-0250903-B1 | Diazabicyclo[3,3,1] nonanes | Kali-Chemie Pharma GmbH (DE) | 1991-11-27 | — | — | EP | disclosed |
| US-4983611-A | TREATING A STOMACH MOTILITY DISTURBANCE | KALI-CHEMIE PHARMA GMBH (DE) | 1991-01-08 | — | — | US | disclosed |
| EP-0212551-B1 | TETRAOXO COMPOUNDS | Kali-Chemie Pharma GmbH (DE) | 1990-10-24 | — | — | EP | disclosed |
| US-4912113-A | Containing a cinnamyl group | KALI-CHEMIE PHARMA GMBH (DE) | 1990-03-27 | — | — | US | disclosed |
| US-4906640-A | 3-sulfonyl-3,7-diazabicyclo[3,3,1]nonane compounds and medicaments containing said compounds | KALI-CHEMIE PHARMA GMBH (DE) | 1990-03-06 | — | — | US | disclosed |
| EP-0103833-B1 | DIAZABICYCLO(3.3.1)NONANES | Kali-Chemie Pharma GmbH (DE) | 1989-08-16 | — | — | EP | disclosed |
| US-4771044-A | ANTIPSYCHOTICS, ANTIDEPRESSANTS AND ANXIOLYTICS | KALI-CHEMIE PHARMA GMBH (DE) | 1988-09-13 | — | — | US | disclosed |
| US-4742172-A | ANTIARRHYTHIMIA | KALI-CHEMIE PHARMA GMBH (DE) | 1988-05-03 | — | — | US | disclosed |
| EP-0250903-A2 | Diazabicyclo[3,3,1] nonanes | Kali-Chemie Pharma GmbH (DE) | 1988-01-07 | — | — | EP | disclosed |
| EP-0212551-A2 | Tetraoxo compounds | Kali-Chemie Pharma GmbH (DE) | 1987-03-04 | — | — | EP | disclosed |
| US-4550112-A | 3,7-Diazabicyclo(3,3,1)nonane compounds and their use in treating heart disease | KALI-CHEMIE PHARMA GMBH (DE) | 1985-10-29 | — | — | US | disclosed |
| EP-0103833-A2 | Diazabicyclo(3.3.1)nonanes | Kali-Chemie Pharma GmbH (DE) | 1984-03-28 | — | — | EP | disclosed |