Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.45 |
| ▸ | SELE | P16581 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826065 | 0.85 | ATM (0.48) | ALDH1A1ATMMAPK1MMP13KMT2A | |
| SCHEMBL4698700 | 0.75 | IKBKB (0.46) | ALDH1A1PARP10PKMBCAT2KMT2A | |
| SCHEMBL7062703 | 0.74 | MEN1 (0.49) | ALDH1A1PARP10PKMMAPK1KMT2A | |
| SCHEMBL14342685 | 0.73 | BCAT2 (0.47) | ALDH1A1PARP10PKMMAPK1BCAT2 | |
| SCHEMBL1379773 | 0.71 | KMT2A (0.68) | ALDH1A1PARP10PKMMAPK1BCAT2 | |
| SCHEMBL2231308 | 0.71 | BCAT2 (0.69) | ALDH1A1PKMATMMAPK1BCAT2 | |
| SCHEMBL25142213 | 0.70 | PARP10 (0.66) | ALDH1A1PARP10MAPK1MMP13KMT2A | |
| SCHEMBL6368241 | 0.70 | CTNNB1 (0.74) | ALDH1A1PARP10MAPK1KMT2AMAPT | |
| SCHEMBL3013339 | 0.70 | PARP10 (0.79) | ALDH1A1PARP10MMP13KMT2APARP15 | |
| SCHEMBL24592196 | 0.70 | PARP10 (0.79) | ALDH1A1PARP10MMP13KMT2APARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249236-B1 | N-1H-TETRAZOL-5-YL-(5-RING)-CARBOXAMIDE-DERIVATIVES, A PROCESS FOR THEIR MANUFACTURE, AND THE USE THEREOF | WARNER-LAMBERT COMPANY (US) | 1991-04-24 | — | — | EP | disclosed |