Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827563 | 0.91 | KDM4E (0.38) | ALDH1A1KDM4EHSD17B10KMT2APOLB | |
| SCHEMBL9826021 | 0.89 | KDM4E (0.33) | ALDH1A1KDM4EHSD17B10RXFP1MAPK1 | |
| SCHEMBL9826175 | 0.88 | KDM4E (0.34) | ALDH1A1KDM4EHSD17B10KMT2APOLB | |
| SCHEMBL9827239 | 0.81 | ALDH1A1 (0.40) | LOXL2ALDH1A1RXFP1KMT2APOLB | |
| SCHEMBL1514052 | 0.78 | SMN1; SMN2 (0.33) | ALDH1A1KDM4E | |
| SCHEMBL27917730 | 0.74 | KDM4E (0.31) | ALDH1A1KDM4ERXFP1 | |
| SCHEMBL9827086 | 0.73 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10KMT2APOLB | |
| SCHEMBL10569137 | 0.71 | CCR4 (0.34) | KDM4EPOLB | |
| SCHEMBL11388959 | 0.69 | LOXL2 (0.34) | LOXL2ALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL9827817 | 0.69 | ALDH1A1 (0.43) | ALDH1A1RXFP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301613-B1 | THIAZOLE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1991-07-10 | — | — | EP | disclosed |
| US-4889863-A | NONPHYTOTOXIC; SEEDS, SOILS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1989-12-26 | — | — | US | disclosed |
| EP-0301613-A1 | Thiazole compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-02-01 | — | — | EP | disclosed |