Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826555 | 0.94 | KDM4E (0.33) | KDM4EHSD17B10 | |
| SCHEMBL9826207 | 0.88 | MAPK1 (0.34) | KDM4EHSD17B10 | |
| SCHEMBL9826788 | 0.77 | SMN1; SMN2 (0.37) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL9826927 | 0.74 | CLK2 (0.33) | KDM4EL3MBTL1 | |
| SCHEMBL11379932 | 0.72 | — | — | |
| SCHEMBL9864685 | 0.72 | MAPT (0.33) | KDM4EHSD17B10 | |
| SCHEMBL11384409 | 0.71 | — | — | |
| SCHEMBL9827347 | 0.71 | NPC1 (0.39) | MEN1KMT2A | |
| SCHEMBL9825848 | 0.70 | MAPK8 (0.34) | KDM4EHSD17B10MEN1TSHRKMT2A | |
| SCHEMBL11861499 | 0.70 | ALDH1A1 (0.49) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301613-B1 | THIAZOLE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1991-07-10 | — | — | EP | disclosed |
| US-4889863-A | NONPHYTOTOXIC; SEEDS, SOILS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1989-12-26 | — | — | US | disclosed |
| EP-0301613-A1 | Thiazole compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-02-01 | — | — | EP | disclosed |