Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 4/20 | 0.39 |
| ▸ | CDK8 | P49336 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825265 | 1.00 | CCNC (0.39) | CCNCCDK8MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9825639 | 0.93 | MAPT (0.38) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9825635 | 0.93 | MAPT (0.38) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9825707 | 0.87 | LMNA (0.40) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9825713 | 0.87 | LMNA (0.40) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3680916 | 0.79 | ALDH1A1 (0.42) | CCNCCDK8MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10924250 | 0.74 | MAPT (0.39) | CCNCCDK8MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10924252 | 0.74 | MAPT (0.39) | CCNCCDK8MAPTALDH1A1SMN1; SMN2 | |
| Ethyl 3-(2,4-Dichlorophenyl)Acrylate SCHEMBL28066301 | 0.72 | LMNA (0.53) | CCNCCDK8MAPTALDH1A1SMN1; SMN2 | |
| Ethyl 3-(2,4-Dichlorophenyl)Acrylate SCHEMBL1895655 | 0.71 | MAPT (0.58) | MAPTALDH1A1SMN1; SMN2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195414-B1 | 2-AZOLYLPROPIONATE DERIVATIVES AND FUNGICIDES CONTAINING THE SAME | SDS Biotech K.K. (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4767752-A | Imidazolyl or triazolyl substituted propionate derivative and nonmedical fungicide containing the same | S.D.S. BIOTECH K.K. (JP) | 1988-08-30 | — | — | US | disclosed |
| EP-0195414-A2 | 2-Azolylpropionate derivatives and fungicides containing the same | SDS Biotech K.K. (JP) | 1986-09-24 | — | — | EP | disclosed |