Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10405323 | 0.80 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2LMNAHTTPOLB | |
| SCHEMBL9825505 | 0.79 | ALDH1A1 (0.60) | ALDH1A1NPC1KMT2AKDM4E | |
| SCHEMBL5071301 | 0.77 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2LMNAHTTPOLB | |
| SCHEMBL8595197 | 0.76 | GSK3A (0.50) | ALDH1A1LMNAHTTPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL3845514 | 0.76 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2LMNAHTTPOLB | |
| SCHEMBL8188406 | 0.76 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2LMNAHTTPOLB | |
| SCHEMBL9826656 | 0.76 | POLB (0.39) | SMN1; SMN2LMNAHTTPOLBMAPT | |
| SCHEMBL9669549 | 0.75 | HPGD (0.62) | ALDH1A1SMN1; SMN2LMNAHTTPOLB | |
| SCHEMBL22803079 | 0.74 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2LMNAHTTPOLB | |
| SCHEMBL8916586 | 0.73 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2LMNAHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203743-B1 | OXOTHIAZOLIDINE COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |
| US-4764514-A | COGNITIONACTIVATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-16 | — | — | US | disclosed |
| EP-0203743-A1 | Oxothiazolidine compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-03 | — | — | EP | disclosed |