Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 4/20 | 0.50 |
| ▸ | GSK3B | P49841 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677830 | 0.82 | GSK3A (0.50) | GSK3AGSK3BL3MBTL1HPGDKMT2A | |
| SCHEMBL14106328 | 0.82 | ALDH1A1 (0.51) | TSHRKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6298744 | 0.82 | L3MBTL1 (0.54) | GSK3AGSK3BL3MBTL1HPGDTSHR | |
| SCHEMBL6208950 | 0.80 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1LMNATDP1 | |
| SCHEMBL9826740 | 0.76 | ALDH1A1 (0.55) | HPGDKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL1488276 | 0.74 | L3MBTL1 (0.56) | GSK3AGSK3BL3MBTL1HPGDTSHR | |
| SCHEMBL9826999 | 0.74 | MAPT (0.53) | HPGDTSHRALDH1A1LMNAPOLB | |
| SCHEMBL7389188 | 0.71 | L3MBTL1 (0.73) | L3MBTL1HPGDTSHRDDB1CRBN | |
| SCHEMBL5642423 | 0.71 | L3MBTL1 (0.62) | GSK3AGSK3BL3MBTL1HPGDTSHR | |
| SCHEMBL11823311 | 0.70 | ALDH1A1 (0.45) | GSK3AGSK3BHPGDTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4937252-A | 2-thiazolidinone derivatives, pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1990-06-26 | — | — | US | claimed |
| CN-101260107-B | Diheterocycle compound containing 4-thiazolidinone and pyrimidine, synthetic method and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2010-12-22 | — | — | CN | disclosed |
| CN-101260107-A | Diheterocycle compound containing 4-thiazolidinone and pyrimidine, synthetic method and application thereof | UNIV ZHEJIANG TECHNOLOGY (CN) | 2008-09-10 | — | — | CN | disclosed |
| WO-1998053790-A2 | COMPOUNDS THAT INHIBIT THE BINDING OF VASCULAR ENDOTHELIAL GROWTH FACTOR TO ITS RECEPTORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1998-12-03 | — | — | WO | disclosed |