Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL834551 | 0.79 | TAAR1 (0.73) | TAAR1MAOBCALM1AOC3SIGMAR1 | |
| SCHEMBL1295195 | 0.79 | TAAR1 (0.55) | TAAR1MAOBCALM1AOC3SIGMAR1 | |
| SCHEMBL1797282 | 0.79 | TAAR1 (0.61) | TAAR1MAOBCALM1AOC3SIGMAR1 | |
| SCHEMBL5254359 | 0.78 | IDO1 (0.52) | TAAR1MAOBCALM1IDO1CA12 | |
| SCHEMBL178692 | 0.78 | TAAR1 (0.64) | TAAR1MAOBCALM1AOC3SIGMAR1 | |
| SCHEMBL7544110 | 0.76 | TAAR1 (0.61) | TAAR1MAOBCALM1AOC3SIGMAR1 | |
| SCHEMBL6835490 | 0.76 | TAAR1 (0.61) | TAAR1MAOBCALM1AOC3SIGMAR1 | |
| SCHEMBL9826743 | 0.76 | TAAR1 (0.61) | TAAR1MAOBCALM1AOC3SIGMAR1 | |
| SCHEMBL250274 | 0.76 | TAAR1 (0.61) | TAAR1MAOBCALM1AOC3SIGMAR1 | |
| SCHEMBL4254058 | 0.75 | CALM1 (0.72) | TAAR1MAOBCALM1AOC3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150892-B1 | SUBSTITUTED ALKYLIDENE IMIDAZOLES | G.D. Searle & Co. (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4837333-A | SELECTIVE INHIBITOR OF THROMBOXANE SYNTHETASE ENZYME | G. D. SEARLE & CO. (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | disclosed |
| EP-0150892-A2 | Substituted alkylidene imidazoles | G.D. Searle & Co. (US) | 1985-08-07 | — | — | EP | disclosed |