SCHEMBL6835490

SCHEMBL6835490

COc1ccc(CC[SiH3])cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.61
MAOB P27338 2/20 0.55
CALM1 P0DP23 2/20 0.55
IDO1 P14902 2/20 0.54
AOC3 Q16853 2/20 0.53
SIGMAR1 Q99720 1/20 0.53
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
F2RL1 P55085 1/20 0.52
TUBB4A P04350 1/20 0.52
TUBB P07437 1/20 0.52
TUBA3C P0DPH7 1/20 0.52
TUBA1B P68363 1/20 0.52
TUBA4A P68366 1/20 0.52
TUBB4B P68371 1/20 0.52
TUBB3 Q13509 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8009496 0.98 TAAR1 (0.59) TAAR1MAOBCALM1IDO1AOC3
SCHEMBL15233009 0.86 CALM1 (0.62) TAAR1MAOBCALM1IDO1AOC3
SCHEMBL834551 0.85 TAAR1 (0.73) TAAR1MAOBCALM1IDO1AOC3
SCHEMBL244070 0.80 CALM1 (0.79) TAAR1MAOBCALM1IDO1AOC3
SCHEMBL4254058 0.80 CALM1 (0.72) TAAR1MAOBCALM1IDO1AOC3
SCHEMBL5163044 0.80 IDO1 (0.58) TAAR1MAOBCALM1IDO1CA12
SCHEMBL17400406 0.78 CALM1 (0.69) TAAR1MAOBCALM1IDO1AOC3
SCHEMBL178692 0.78 TAAR1 (0.64) TAAR1MAOBCALM1IDO1AOC3
SCHEMBL11007798 0.78 CALM1 (0.69) TAAR1MAOBCALM1IDO1AOC3
SCHEMBL91277 0.78 TAAR1 (0.64) TAAR1MAOBCALM1IDO1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119192218-A Preparation method of alkyl trihydrosilane and methyl alkyl dihydrosilane 中国科学院兰州化学物理研究所 2024-12-27 CN disclosed
CN-110343128-B Method for preparing silane through hydrosilation reaction 中国科学院化学研究所 2021-02-19 CN disclosed
CN-110343128-A A method of silane is prepared by silicon hydrogenation 中国科学院化学研究所 2019-10-18 CN disclosed
US-6753401-B1 DEHYDROGENATIVE POLYMERIZATION OF QUINONE AND/OR DIOL WITH TRIHYDROSILANE OR DIHYDROSILANE IN PRESENCE OF PALLADIUM-CONTAINING CATALYST; POLYSILANES NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2004-06-22 US disclosed
EP-1234829-A1 SILICON-CONTAINING POLYMERS National Institute of Advanced Industrial Science and Technology (JP) 2002-08-28 EP disclosed