Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598760 | 0.91 | TGM2 (0.45) | TGM2TSHRSMN1; SMN2LMNAMEN1 | |
| SCHEMBL4934993 | 0.87 | TGM2 (0.49) | TGM2 | |
| SCHEMBL4934061 | 0.87 | TGM2 (0.49) | TGM2 | |
| SCHEMBL4598577 | 0.86 | TGM2 (0.44) | TGM2SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL9825628 | 0.84 | TGM2 (0.40) | TGM2TSHRSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL4598860 | 0.84 | TGM2 (0.42) | TGM2SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL9826313 | 0.83 | TGM2 (0.42) | TGM2 | |
| SCHEMBL9825676 | 0.83 | TGM2 (0.47) | TGM2TSHR | |
| SCHEMBL4950332 | 0.82 | TGM2 (0.47) | TGM2TSHR | |
| SCHEMBL9826686 | 0.82 | TGM2 (0.41) | TGM2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237082-B1 | 3,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOLES AS TRANSGLUTAMINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1991-05-29 | — | — | EP | claimed |