SCHEMBL982740

SCHEMBL982740

CC(C)CC(C)O[Si](OC(C)CC(C)C)(OC(C)CC(C)C)OC(C)CC(C)C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP19A1 P11511 1/20 0.31
RNPEP Q9H4A4 1/20 0.31
SLC7A5 Q01650 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1123623 0.88 ALDH1A1 (0.30) ALDH1A1TSHRMAPK1
SCHEMBL843254 0.79 TSHR (0.32) ALDH1A1TSHRMAPK1CYP19A1
SCHEMBL28069258 0.78
SCHEMBL10602864 0.77 RNPEP (0.33) ALDH1A1TSHRMAPK1CYP19A1RNPEP
SCHEMBL1638798 0.77 ALDH1A1 (0.30) ALDH1A1TSHRMAPK1
SCHEMBL9262022 0.75
SCHEMBL1508172 0.71
SCHEMBL285341 0.71 TSHR (0.32) TSHR
SCHEMBL887748 0.69 MAPK1 (0.44) ALDH1A1TSHRMAPK1CYP19A1RNPEP
SCHEMBL444987 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11389784-B2 Next generation modified silica materials for increased performance and industrial applications SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-07-19 US disclosed
EP-1894988-B1 Tetraoxy-silane lubricating oil compositions CHEVRON ORONITE CO (US) 2020-04-15 EP disclosed
US-20190351400-A1 NEXT GENERATION MODIFIED SILICA MATERIALS FOR INCREASED PERFORMANCE AND INDUSTRIAL APPLICATIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-11-21 US disclosed
US-8933001-B2 Method for improving fluorocarbon elastomer seal compatibility CHEVRON ORONITE COMPANY LLC (US) 2015-01-13 US disclosed
US-8901050-B2 Method for improving copper corrosion performance CHEVRON ORONITE COMPANY LLC (US) 2014-12-02 US disclosed
EP-2553062-A2 METHOD FOR IMPROVING COPPER CORROSION PERFORMANCE Chevron Oronite Company LLC (US) 2013-02-06 EP disclosed
US-8153566-B2 Lubricating oil compositions Cherron Oronite Company LLC (US) 2012-04-10 US disclosed
US-8067346-B2 Phosphorus and sulfur free; friction reduction; safe for catalytic converters; environmentally friendly; engine lifetime CHEVRON ORONITE COMPANY LLC (US) 2011-11-29 US disclosed
WO-2011126642-A2 METHOD FOR IMPROVING COPPER CORROSION PERFORMANCE CHEVRON ORONITE COMPANY LLC (US) 2011-10-13 WO disclosed
US-20110239971-A1 Method for improving copper corrosion performance CHEVRON ORONITE COMPANY LLC (US) 2011-10-06 US disclosed
US-20110245118-A1 Method for improving fluorocarbon elastomer seal compatibility CHEVRON ORONITE COMPANY LLC (US) 2011-10-06 US disclosed
EP-2337830-A2 LUBRICATING OIL COMPOSITION Chevron Oronite Company LLC (US) 2011-06-29 EP disclosed
US-7867960-B2 Method for forming tetraoxy-silane derived antiwear films and lubricating oil compositions therefrom Cherron Oronite Company LLC (US) 2011-01-11 US disclosed
WO-2010039599-A2 LUBRICATING OIL COMPOSITION CHEVRON ORONITE COMPANY LLC (US) 2010-04-08 WO disclosed
US-20100081588-A1 Lubricating oil compositions CHEVRON ORONITE COMPANY LLC (US) 2010-04-01 US disclosed
US-20080058232-A1 Tetraoxy-silane lubricating oil compositions CHEVRON ORONITE COMPANY LLC 2008-03-06 US disclosed
US-20080058231-A1 Method for forming tetraoxy-silane derived antiwear films and lubricating oil compositions therefrom CHEVRON ORONITE COMPANY LLC 2008-03-06 US disclosed
EP-1894986-A2 Method for forming tetraoxy-silane derived antiwear films and lubricating oil compositions therefrom Chevron Oronite Company LLC (US) 2008-03-05 EP disclosed
EP-1894988-A2 Tetraoxy-silane lubricating oil compositions Chevron Oronite Company LLC (US) 2008-03-05 EP disclosed