Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29133639 | 0.77 | TGM2 (0.30) | TGM2ALDH1A1 | |
| SCHEMBL29701951 | 0.73 | ALDH1A1 (0.47) | KMT2ATGM2ALDH1A1NPC1RAB9A | |
| SCHEMBL9827386 | 0.73 | TGM2 (0.39) | L3MBTL1MEN1KMT2ATGM2ALDH1A1 | |
| SCHEMBL9440877 | 0.70 | SMN1; SMN2 (0.48) | L3MBTL1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2098175 | 0.70 | ALDH1A1 (0.42) | L3MBTL1KMT2ATP53HBBSMN1; SMN2 | |
| SCHEMBL31262919 | 0.70 | ALDH1A1 (0.42) | KMT2ATP53HBBSMN1; SMN2ALDH1A1 | |
| SCHEMBL5536073 | 0.70 | ALDH1A1 (0.42) | L3MBTL1KMT2ATP53HBBSMN1; SMN2 | |
| SCHEMBL10677125 | 0.70 | ALDH1A1 (0.60) | KMT2ATP53HBBSMN1; SMN2ALDH1A1 | |
| SCHEMBL23403970 | 0.69 | ALDH1A1 (0.37) | TGM2ALDH1A1PRMT5 | |
| SCHEMBL30116052 | 0.69 | ALDH1A1 (0.37) | MEN1KMT2ATGM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212558-B1 | A RADIATION SENSITIZER | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1991-12-04 | — | — | EP | disclosed |
| US-4820844-A | 2-(3'-NITRO-1'-TRIAZOLYL) ACETIC ACID ETHANOL AMIDE | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1989-04-11 | — | — | US | disclosed |
| EP-0212558-A2 | A radiation sensitizer | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1987-03-04 | — | — | EP | disclosed |