SCHEMBL9827604

SCHEMBL9827604

O=C1c2ccccc2C(=O)N1CCCNCCCCNCCCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 11/20 0.69
SIRT1 Q96EB6 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9218494 0.98 ACHE (0.66) ACHESIRT1
SCHEMBL7476248 0.94 SIRT1 (0.66) ACHESIRT1
SCHEMBL7946668 0.93 ACHE (0.74) ACHESIRT1
SCHEMBL16573400 0.91 ACHE (0.59) ACHESIRT1
SCHEMBL28430378 0.90 ACHE (0.57) ACHESIRT1
SCHEMBL28369359 0.90 ACHE (0.57) ACHESIRT1
SCHEMBL16317302 0.88 ACHE (0.56) ACHESIRT1
SCHEMBL21309370 0.87 ACHE (0.59) ACHESIRT1
SCHEMBL24686952 0.87 ACHE (0.67) ACHESIRT1
SCHEMBL30061850 0.87 ACHE (0.67) ACHESIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0220409-B1 GEM-DIHALO AND TETRAHALO-1,12-DIAMINO-4,9-DIAZA-DODECANES MERRELL DOW PHARMACEUTICALS INC. (US) 1991-11-27 EP claimed
EP-0220409-A2 Gem-dihalo and tetrahalo-1,12-diamino-4,9-diaza-dodecanes MERRELL DOW PHARMACEUTICALS INC. (US) 1987-05-06 EP claimed
WO-2026102133-A1 MULTIVALENT IONIZABLE LIPID DELIVERY SYSTEMS FACTOR BIOSCIENCE INC. (US) 2026-05-15 WO disclosed
EP-4705273-A2 MULTIVALENT IONIZABLE LIPID DELIVERY SYSTEMS Factor Bioscience Inc. (US) 2026-03-11 EP disclosed
WO-2024229032-A2 MULTIVALENT IONIZABLE LIPID DELIVERY SYSTEMS FACTOR BIOSCIENCE INC. (US) 2024-11-07 WO disclosed