Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.58 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830722 | 0.94 | HTT (0.63) | HTTSMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL9828606 | 0.87 | HTT (0.65) | HTTSMN1; SMN2LMNATSHRHDAC3 | |
| SCHEMBL4922485 | 0.85 | SMN1; SMN2 (0.60) | HTTSMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL23120359 | 0.84 | CHRNB2 (0.62) | HTTSMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL4910211 | 0.84 | SMN1; SMN2 (0.61) | HTTSMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL319161 | 0.83 | HTT (1.00) | HTTSMN1; SMN2LMNAHDAC3HDAC4 | |
| SCHEMBL19438762 | 0.82 | CHRNB2 (0.64) | HTTSMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL1836192 | 0.81 | CHRNB2 (0.59) | HTTSMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL25447800 | 0.81 | CHRNB2 (0.59) | HTTSMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL4920505 | 0.81 | CHRNB2 (0.56) | HTTSMN1; SMN2NPC1RECQLRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |