Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828063 | 0.89 | SLC6A2 (0.43) | CHEK2CYP2C9SLC6A2SLC6A4HTR3A | |
| SCHEMBL20376278 | 0.80 | MEN1 (0.55) | CHEK2CYP2C9CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL21325041 | 0.80 | CYP2C9 (0.49) | CHEK2CYP2C9CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL917239 | 0.79 | NPC1 (0.61) | CHEK2CYP2C9CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL17292671 | 0.78 | NPC1 (0.59) | CHEK2CYP2C9CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL16134548 | 0.77 | LMNA (0.51) | CYP2C9CYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL4825999 | 0.74 | CYP3A4 (0.54) | CHEK2CYP2C9CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL21017784 | 0.74 | CHEK2 (0.57) | CHEK2NPC1RAB9AHPGDMAPT | |
| SCHEMBL29770426 | 0.73 | NPC1 (0.58) | CYP2C9CYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL26189984 | 0.73 | NPC1 (0.40) | CYP2C9CYP1A2CYP2E1CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240158-B1 | BENZIMIDAZOLE DERIVATIVES | TOKYO TANABE COMPANY LIMITED (JP) | 1991-04-03 | — | — | EP | claimed |
| EP-0240158-A1 | Benzimidazole derivatives | TOKYO TANABE COMPANY LIMITED (JP) | 1987-10-07 | — | — | EP | claimed |
| EP-0240158-B1 | BENZIMIDAZOLE DERIVATIVES | TOKYO TANABE COMPANY LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4753955-A | ANTIULCER | TOKYO TANABE COMPANY, LTD. (JP) | 1988-06-28 | — | — | US | disclosed |
| EP-0240158-A1 | Benzimidazole derivatives | TOKYO TANABE COMPANY LIMITED (JP) | 1987-10-07 | — | — | EP | disclosed |