Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828070 | 0.89 | CHEK2 (0.47) | SLC6A2SLC6A4PARP15PARP10HTR3A | |
| SCHEMBL917237 | 0.79 | HSD17B10 (0.49) | — | |
| SCHEMBL17292670 | 0.78 | HSD17B10 (0.47) | — | |
| SCHEMBL16134720 | 0.77 | KDM4E (0.43) | CYP2C9 | |
| SCHEMBL8304476 | 0.75 | CACNA1B (0.40) | MAOBCYP2C9 | |
| SCHEMBL4825992 | 0.74 | CYP3A4 (0.54) | MAOAMAOBCYP2C9 | |
| SCHEMBL10267514 | 0.74 | MAOA (0.45) | SLC6A2SLC6A4PARP15PARP10HTR3A | |
| SCHEMBL916531 | 0.73 | ALDH1A1 (0.48) | CYP2C9 | |
| SCHEMBL10485069 | 0.72 | PDE5A (0.40) | KCNH2PDE4APDE4D | |
| SCHEMBL7409754 | 0.72 | F10 (0.54) | CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240158-B1 | BENZIMIDAZOLE DERIVATIVES | TOKYO TANABE COMPANY LIMITED (JP) | 1991-04-03 | — | — | EP | claimed |
| EP-0240158-A1 | Benzimidazole derivatives | TOKYO TANABE COMPANY LIMITED (JP) | 1987-10-07 | — | — | EP | claimed |
| EP-0240158-B1 | BENZIMIDAZOLE DERIVATIVES | TOKYO TANABE COMPANY LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4753955-A | ANTIULCER | TOKYO TANABE COMPANY, LTD. (JP) | 1988-06-28 | — | — | US | disclosed |
| EP-0240158-A1 | Benzimidazole derivatives | TOKYO TANABE COMPANY LIMITED (JP) | 1987-10-07 | — | — | EP | disclosed |