Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 3/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 3/20 | 0.39 |
| ▸ | ADA | P00813 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13787734 | 0.87 | ALDH1A1 (0.56) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL9826496 | 0.87 | ALDH1A1 (0.59) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL3364 | 0.84 | ALDH1A1 (0.61) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL1769151 | 0.84 | ALDH1A1 (0.61) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL12150307 | 0.84 | ALDH1A1 (0.61) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| SCHEMBL10438025 | 0.83 | ALDH1A1 (0.57) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL7910803 | 0.83 | ALDH1A1 (0.60) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL8709115 | 0.83 | ALDH1A1 (0.60) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL7910809 | 0.83 | ALDH1A1 (0.60) | ALDH1A1LMNAALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL7907423 | 0.82 | ALDH1A1 (0.59) | ALDH1A1LMNAALBMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3148278-A | — | — | None | — | — | JP | disclosed |
| US-9186369-B2 | Purine nucleoside analogues for treating flaviviridae including hepatitis C | IDENIX PHARMACEUTICALS, LLC (US) | 2015-11-17 | — | — | US | disclosed |
| US-20140234251-A1 | PURINE NUCLEOSIDE ANALOGUES FOR TREATING FLAVIVIRIDAE INCLUDING HEPATITIS C | INDENIX PHARMACEUTICALS, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| US-8742101-B2 | Purine nucleoside analogues for treating flaviviridae including hepatitis C | IDENIX PHARMACEUTICALS, INC. (US) | 2014-06-03 | — | — | US | disclosed |
| JP-H03148278-A | NOVEL NUCLEOSIDE AND PRODUCTION THEREOF | NIPPON KAYAKU CO LTD | 1991-06-25 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140234251-A1 | PURINE NUCLEOSIDE ANALOGUES FOR TREATING FLAVIVIRIDAE INCLUDING HEPATITIS C | PNP, TPMT, MTAP | ALDH1A1 1160/4885LMNA 2831/4885ALB 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.