Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9828346 | 0.99 | FFAR1 (0.40) | FFAR1FFAR4CYP2D6CYP2C19HDAC1 | |
| SCHEMBL9827728 | 0.92 | FFAR1 (0.35) | FFAR1FFAR4CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL9827657 | 0.91 | FFAR1 (0.34) | FFAR1FFAR4CYP2D6CYP2C19 | |
| SCHEMBL9828326 | 0.90 | HRH4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL9827568 | 0.89 | GRIN2D (0.33) | — | |
| SCHEMBL9828412 | 0.85 | CHRM2 (0.46) | CYP2D6CYP2C19 | |
| SCHEMBL7287544 | 0.84 | HRH1 (0.41) | CYP2C19 | |
| SCHEMBL9829110 | 0.84 | SIGMAR1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL9827919 | 0.84 | LMNA (0.47) | CYP2D6CYP2C19 | |
| SCHEMBL9827932 | 0.82 | CYP2D6 (0.50) | CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302896-B1 | N-(W-SUBSTITUTED ALKYL)-N'-[(IMIDAZOLE-4-YL)ALKYL]GUANIDINE | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-08-14 | — | — | EP | claimed |